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Description
PELP1 Recombinant Rabbit mAb (S-756-22)Product Specification Host Rabbit Synonyms Proline , glutamic acid and leucine rich protein 1, Modulator of non genomic activity of estrogen receptor, Transcription factor HMX3, HMX3, MNAR Immunogen Synthetic Peptide Location Cytoplasm, Nucleus Accession Q8IZL8 Clone Number S 756 22 Antibody Type Recombinant mAb Isotype IgG Application WB, IHC P, ICC, ICFCM, IP Reactivity Hu Purification Protein A Concentration 0. 5 mg ml Conjugation Unconjugated
Product Specification
| Host | Rabbit |
| Synonyms | Proline-, glutamic acid- and leucine-rich protein 1, Modulator of non-genomic activity of estrogen receptor, Transcription factor HMX3, HMX3, MNAR |
| Immunogen | Synthetic Peptide |
| Location | Cytoplasm, Nucleus |
| Accession | Q8IZL8 |
| Clone Number | S-756-22 |
| Antibody Type | Recombinant mAb |
| Isotype | IgG |
| Application | WB, IHC-P, ICC, ICFCM, IP |
| Reactivity | Hu |
| Purification | Protein A |
| Concentration | 0.5 mg/ml |
| Conjugation | Unconjugated |
| Physical Appearance | Liquid |
| Storage Buffer | PBS, 40% Glycerol, 0.05% BSA, 0.03% Proclin 300 |
| Stability & Storage | 12 months from date of receipt / reconstitution, -20 °C as supplied |
Dilution
| application | dilution | species |
| WB | 1:1000 | |
| IHC-P | 1:2000 | |
| ICC | 1:500 | |
| ICFCM | 1:500 | |
| IP | 1:50 |
Background
Proline-, glutamic acid-, and leucine-rich protein 1 (PELP1) is transcription coregulator and modulates functions of several hormonal receptors and transcription factors. PELP1 plays essential roles in hormonal signaling, cell cycle progression, and ribosomal biogenesis. PELP1 expression is upregulated in several cancers; its deregulation contributes to hormonal therapy resistance and metastasis; therefore, PELP1 represents a novel therapeutic target for many cancers.
Shipping Notes
- Free Standard Shipping on $100+ Orders to the USA.
- Except Preorder products are shipped in 48 hours.
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- Standard Shipping : 3-10 business days
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Exchange/Return Notes
- We offer a 30-day return/exchange service after receiving.
- Final sale items are not eligible for returns or exchanges.
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4.8 ★★★★★
Based on 749 reviews
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Product Reviews
★★★★★ 1
Burned my already sensitive feet, too big
Color: Pink & Beige, Size: Medium/Large(fits size 8 to 11)
Feels icky, and the heat gets trapped and literally felt like my feet were being burned by these. The bottoms of these feel prickly and they are way too big. You have to sit still and cannot walk in them.
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Reviewed in the United States on April 22, 2026
★★★★★ 5
Just as good as paraffin wax
Color: Pink & Beige, Size: Medium/Large(fits size 8 to 11)
I might prefer these socks over paraffin wax. They are comfy and very moisturizing. I use these socks once a week to keep the heels and soles of my feet moisturized between pedicures. I rinse with warm, soapy water then hang to dry. They are hard to walk in, but there's a saying printed in the socks that's says something to the effect of "take a break, stay off your feet" lol I love that as a reminder to put my feet up and relax
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Reviewed in the United States on April 9, 2026
★★★★★ 5
Love these!
Color: Pink & Beige, Size: Small(fits up to size 7)
Love these! As I write this review, I’m sitting in my recliner with these on. I have had other silicone socks in the past and would like to share a few of the things that I have learned.
These fit great! The others were 2-3 sizes too big because you could not order a size. I wear a size 7 women’s shoe. I got the smaller size. I walked around my apartment in my old ones and they got kinda yucky. Now, I sit in my recliner, put them on and chill for a few hours. I now take them off and put in a ziplock bag so they stay nice and clean (no cat hair!). I use them once a week usually on Saturday or Sunday as I’m a working girl. Also, I use Auqaphor before I put them on and put cotton socks on after I’m finished. Your feet will be SO soft. This is not a one and done…I do this every week especially during sandal season! I know this was lengthy and I hope you got some tips.
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Reviewed in the United States on April 25, 2026
★★★★★ 5
The dogs like it very much, it produces a lot of noise.
Size: Large, Size: Large
I’m rating this based on my dogs’ response to this toy – they absolutely love it, and it has seen more use without damage than any of their regular throwing toys. At the same time, unless you enjoy, REALLY ENJOY the sound of crunching water bottles, you may not like having this ball in the house.
Pros:
The rubber outer shell of the ball is durable, and can survive both chewing and pulling forces (as a note, my dogs do not concentrate on chewing - they use it more for play games). It’s big enough for my dogs to play tug of war with it, hooking their teeth in the mesh, and they since it bounces around if they drop or kick it, it makes the game more interesting than rope. They did crush the interior plastic, but they don't really seem to care.
It’s much more engaging than a normal ball, and can be modified to hold treats, sticks, rope elements and other external bits, which my shepherd mix loves; he gets bored easily and frequently, and this can actually entertain him.
Cons:
This toy is loud, and produces repetitive crunching sounds. It is apparently really engaging to chew, and my dogs will produce the horrid plastic crackling up to half an hour at a time. If you let your dogs in and out, it would make a fine outdoor toy, but since I have a dog door, it migrates around to pretty much wherever the dogs are. I kind of hate it, but will probably buy another if they break this one since they enjoy it so much.
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Reviewed in the United States on October 17, 2016
★★★★★ 5
Very durable and my Heeler's fave inside toy
Size: Large
My red Heeler loves these balls, second only to Tennis balls but she destroys those within minutes and they are outside only. This is her inside ball. She is hard on toys and has the strongest bite of any dog I've had (shepherds, collies, weimaraners, retrievers, Labs) yet these continue to last. She catches the ball, we play tug of war with it (she places it in hand hand and pulls only when I have a firm grip, she shakes it and flings it. The rubber outside even outlasts the water-bottle like plastic piece inside. Steps holds the ball with her foot and pulls on the rubber with her mouth, stretching it to sometimes twice its size. I pull while shes pulling. This thing gets abused daily and keeps on going. Its the most used toy and she brings it to me to play with every day. Each ball lasts about 6 months before the inside ball is toast and the outer rubber is finally starting to tear/break. which for me in an incredibly long time. If this ball is available to play, she wants it over all others. Shes NEVER gotten a piece off to actually swallow and that alone is worth the price.
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Reviewed in the United States on June 4, 2025
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