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Description
Calreticulin Recombinant Rabbit mAb (S-R353)Product Specification Host Rabbit Synonyms CRP55, Calregulin, Endoplasmic reticulum resident protein 60 (ERp60), HACBP, grp60, CALR, CRTC Location Cytoplasm, Secreted Accession P27797 Clone Number S R353 Antibody Type Recombinant mAb Isotype IgG Application WB, IHC P, ICC, ICFCM Reactivity Hu Purification Protein A Concentration 0. 5 mg ml Conjugation Unconjugated Physical Appearance Liquid Storage Buffer PBS, 40% Glycerol, 0. 05% BSA, 0. 03% Proclin
Product Specification
| Host | Rabbit |
| Synonyms | CRP55, Calregulin, Endoplasmic reticulum resident protein 60 (ERp60), HACBP, grp60, CALR, CRTC |
| Location | Cytoplasm, Secreted |
| Accession | P27797 |
| Clone Number | S-R353 |
| Antibody Type | Recombinant mAb |
| Isotype | IgG |
| Application | WB, IHC-P, ICC, ICFCM |
| Reactivity | Hu |
| Purification | Protein A |
| Concentration | 0.5 mg/ml |
| Conjugation | Unconjugated |
| Physical Appearance | Liquid |
| Storage Buffer | PBS, 40% Glycerol, 0.05% BSA, 0.03% Proclin 300 |
| Stability & Storage | 12 months from date of receipt / reconstitution, -20 °C as supplied. |
Dilution
| application | dilution | species |
| WB | 1:1000-1:10000 | null |
| IHC-P | 1:2000 | null |
| ICC | 1:500 | null |
| ICFCM | 1:500 | null |
Background
Calreticulin is a multifunctional soluble protein that binds Ca2+ ions (a second messenger in signal transduction), rendering it inactive. The Ca2+ is bound with low affinity, but high capacity, and can be released on a signal (see inositol trisphosphate). Calreticulin is located in storage compartments associated with the endoplasmic reticulum and is considered an ER resident protein. Calreticulin also binds to misfolded proteins and prevents them from being exported from the endoplasmic reticulum to the Golgi apparatus.
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Exchange/Return Notes
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4.4 ★★★★★
Based on 1902 reviews
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Product Reviews
★★★★★ 4
Excellent Formula, but the Product Runs Out Far Too Quickly
Style: MULTIBALM
The balm is genuinely hydrating, smooth, and very convenient to use. It applies beautifully, gives the skin a healthy glow, and works well on dry areas, lips, and the face overall. The texture feels comfortable and nourishing without feeling overly heavy or greasy.
My only major disappointment is the value for the price. Even using a very thin layer across the face once each evening, one stick lasted only about a week. I purchased two of them, and both were exactly the same, so this was clearly not an issue with a defective or partially filled tube.
If you intend to use it regularly over the full face, expect it to run out extremely quickly. I purchased mine during a significant sale, and even at the discounted price I still felt disappointed by how little use I got from it.
Overall, the formula performs well, but the quantity does not justify the regular price for consistent daily use.
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Reviewed in the United States on May 24, 2026
★★★★★ 5
Youthful, even skin!
Style: MULTIBALM
I’m loving this stick! I almost sent it back after the first two days but I’m so glad I didn’t. This has really helped me look more refreshed. It’s def helped with shallow lines. Overall it’s made me skin more even. It’s very oily and it sits on your skin so I use it before bed. But I’ve noticed it’s helped balance my skin. I usually get really oily during the day but oddly as oily as this is it keeps my skin from getting oily during the day under my makeup. My makeup looks more even. It’s just overall been great for my skin and it’s made me look younger. Def recommend!
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Reviewed in the United States on May 21, 2026
★★★★★ 3
Hydrating moisturizer with pleasant scent
Style: MULTIBALM
Update:
I’ve now used 2 sticks. I won’t be buying again. Although I like how convenient this moisturizer is, the price is too high for the amount you get. Also, going through another stick, I’ve noticed no signs that it helps with fine lines or wrinkles. This product is simply an on the go moisturizer or even a highlighter. But I can use castor oil and Vaseline for that. I had to deduct a star.
So far, this moisturizing stick has been a great and convenient addition to my routine. It glides on smoothly and has a light, pleasant scent. The formula is definitely hydrating and leaves my skin feeling soft.
It does go on a bit oily or greasy at first. If that bothers you, rubbing it in helps, though it doesn't absorb immediately—so expect a bit of shine for a while after application.
As a moisturizer, it works well and I would definitely recommend it for anyone looking for a quick, on-the-go option. I haven’t noticed any additional benefits yet (like long-term improvements in skin texture or tone), but it might be too early to say. I’ll update my review if anything changes with continued use.
I do have a couple of concerns. First, the price—it feels expensive for the amount of product you get. Second, I’ve seen some people compare this to Botox, and I’m not sure why. It’s definitely not a substitute, and expecting those kinds of results just isn’t realistic. Along those lines, the product name—“Wrinkle Bounce”—may be a little misleading. While it’s hydrating and may temporarily plump the skin, it doesn’t deliver dramatic wrinkle-reducing effects.
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Reviewed in the United States on June 2, 2025
★★★★★ 5
Great Product!
Style: MULTIBALM
After reading many reviews I decided to try this product, my skin is dry with oily areas plus as I get older I have patchy small discolored areas.
I love this product!
After a few days of putting this on first thing am after washing my face, I found it balanced my skin beautifully! After washing my face to get ready for work, I discovered my makeup goes on so much more smoother, and stays in place without having to touch up constantly. It doesn’t remove wrinkles but definitely makes my skin smoother and wrinkles gentle versus distinctive.
Great product!
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Reviewed in the United States on May 13, 2026
★★★★★ 4
Wrinkles: Meh, KP: Yeah!
Style: MULTIBALM, Style: MULTIBALM
An okay moisturizer. Very shiny. Scent is old fashioned - kind of a floral baby powder scent. Takes a while to soak in which is by design since it only fills in the wrinkles instead of plumping them. The illusion is in the shine. You can see from my photos that in certain light the wrinkles appear slightly diminished due to the shine but you can clearly see they are still there in the shadows. While this example is on my hand, I had the same results under my eyes and on my forehead. I let the product soak in for 5 minutes in these photos. On the upside it worked temporary wonders on my KP!
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Reviewed in the United States on May 19, 2026
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